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G. S. Pant (auth.), Magdy M. Khalil (eds.)'s Basic Sciences of Nuclear Medicine PDF

By G. S. Pant (auth.), Magdy M. Khalil (eds.)

ISBN-10: 3540859616

ISBN-13: 9783540859611

ISBN-10: 3540859624

ISBN-13: 9783540859628

Nuclear medication has develop into an ever-changing and increasing diagnostic and healing clinical career. The daily recommendations visible within the box are, in nice half, as a result integration of many medical bases with advanced technologic advances. the purpose of this reference ebook, uncomplicated Sciences of Nuclear drugs, is to supply the reader with a accomplished and specified dialogue of the clinical bases of nuclear drugs, protecting the several issues and ideas that underlie some of the investigations and approaches played within the box. themes contain radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and puppy chemistry, radiobiology and radiation dosimetry, snapshot processing, snapshot reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.

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8 Strontium-89 . . . . . . . . . . . . . . . . . 9 Rhenium-186 . . . . . . . . . . . . . . . . 10 Samarium-153 . . . . . . . . . . . . . . . . 11 111In- and 90Y-Ibritumomab Tiuxetan (Zevalin) . . . . . . . . . . . . . . 12 90Y-Labeled Microspheres . . . . . . . . . . 13 Lutetium-177 Compounds . . . . . . . . . . 37 References . . . . . . . . . . . . . . . . . . . . . . . . . 1 Introduction A radiopharmaceutical is a radioactive compound that has two components, a radionuclide and a pharmaceutical; it is used for the diagnosis and treatment of human diseases.

SPECT and PET radiopharmaceuticals have a wide acceptance in molecular imaging, biomedical research disciplines, and drug development. S. Food and Drug Administration (FDA), widely available, well reviewed in the literature, and relatively cheaper and perform for a significant patient population on a daily basis, whereas this situation is not true for the use of PET compounds. SPECT radiotracers have a particular position in the matrix of molecular imaging due to their ability to image endogenous ligands such as peptides and antibodies and their ability to measure relatively slow kinetic processes due to the relatively long halflife of the commonly used isotopes (in comparison to PET).

Radiation injuries are rarely life threatening to the victim and the attending physician/staff.  Clean the wound with mild detergent and flush with isotonic saline or water. If necessary, a topical anesthetic, such as 4% lidocaine, can be used to allow more vigorous cleansing. After a reasonable effort, there is no need to attempt to remove all contamination since it will probably be incorporated into the scab.  Whenever radionuclides have entered the skin via a needle or sharps, induce the wound to bleed by “milking” it as a cleansing action in addition to the use of running water.

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Basic Sciences of Nuclear Medicine by G. S. Pant (auth.), Magdy M. Khalil (eds.)

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